Solubility: Soluble in water to 1 mg/mL
Notes: also referred to as Glucose-dependent insulinotropic polypeptide
Gastric inhibitory polypeptide (GIP) is part of the incretin family of hormones that regulate blood glucose levels. GIP lowers blood glucose levels by stimulating an increase in insulin levels. As such, GIP is an essential regulator of insulin secretion and glucose homeostasis. It is a high affinity agonist of its receptor (EC50 = 0.81 nM) that inhibits gastric acid secretion and stimulates pancreatic insulin release in response to glucose. GIP has also been shown to affect lipid metabolism and exhibit mitogenic and antiapoptotic effects in pancreatic β-cells.
Each peptide comes complete with the following information:
a QC summary sheet
two reverse phase HPLC profiles to verify purity
mass spectrometry to verify molecular weight
amino acid analysis to verify composition
We use outside laboratories to provide the amino acid analysis and mass spectrometry. This third-party verification allows us to remain objective and has helped us achieve an excellent record of delivering top quality peptides since 1993.